FBXO38 Drives PD-1 to Destruction. Issue 2 (February 2019)
- Record Type:
- Journal Article
- Title:
- FBXO38 Drives PD-1 to Destruction. Issue 2 (February 2019)
- Main Title:
- FBXO38 Drives PD-1 to Destruction
- Authors:
- Serman, Taryn M.
Gack, Michaela U. - Abstract:
- Abstract : Aberrant expression of T cell-resident programmed cell death protein-1 (PD-1) is known to promote tumor progression. A recent study ( Nature 2018;564:130–135) has now identified the E3 ubiquitin ligase FBXO38 as a crucial regulator of PD-1 protein turnover in T cells, providing a novel mechanism for potential use in cancer immunotherapy.
- Is Part Of:
- Trends in immunology. Volume 40:Issue 2(2019)
- Journal:
- Trends in immunology
- Issue:
- Volume 40:Issue 2(2019)
- Issue Display:
- Volume 40, Issue 2 (2019)
- Year:
- 2019
- Volume:
- 40
- Issue:
- 2
- Issue Sort Value:
- 2019-0040-0002-0000
- Page Start:
- 81
- Page End:
- 83
- Publication Date:
- 2019-02
- Subjects:
- Immunology -- Periodicals
571.96 - Journal URLs:
- http://www.sciencedirect.com/science/journal/14714906 ↗
http://www.elsevier.com/journals ↗ - DOI:
- 10.1016/j.it.2018.12.005 ↗
- Languages:
- English
- ISSNs:
- 1471-4906
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 9049.630500
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 9460.xml