Developmental outcome in a group of twins: Relation to perinatal factors and general movements. (July 2018)

• Record Type: Journal Article
• Authors: Dostanic, Tamara; Sustersic, Breda; Paro-Panjan, Darja
• Is Part Of: European journal of paediatric neurology. Volume 22:Number 4(2018:Jul.)
• Page Start: 682
• Page End: 689
• Publication Date: 2018-07
• Subjects: Twins -- Newborn -- Preterm -- General movements -- Development; GMs general movements -- GA gestational age -- IQR interquartile range -- ART assisted reproductive technology -- CP cerebral palsy -- DD dichorionic diamniotic -- MD monochorionic diamniotic -- MM monochorionic monoamniotic -- SGA small for gestational age -- N normal -- PR poor repertoire -- CS cramped synchronized -- Ch chaotic -- F + NOR normal fidgety with normal other repertoire -- F + AOR normal fidgety with abnormal other repertoire -- AF abnormal fidgety movements -- F absence of fidgety movements -- MND minor neurological dysfunction -- WPPSI-III Wechsler Preschool and Primary Scale of Intelligence – Third edition -- WISC III Wechsler Intelligence Scales for Children – Third Edition -- ABAS-II The Adaptive Behaviour Assessment System – Second Edition -- VMI Developmental Test of Visual-Motor Integration -- BSID II Bayley Scales of Infant Development - Second Edition -- CBCL Child Behaviour Check list; Pediatric neurology -- Periodicals; Nervous System Diseases -- Periodicals; Child -- Periodicals; Infant -- Periodicals; Neurologie pédiatrique -- Périodiques; Pediatric neurology; Electronic journals; Periodicals; Electronic journals; 618.928
• DOI: 10.1016/j.ejpn.2018.04.006
• Languages: English
• ISSNs: 1090-3798

Abstract

Abstract: Background: The quality of general movements (GMs) has proven to have predictive value for the developmental outcome, but this has not yet been studied in twins. Aims: Our aim was to analyse the quality of GMs and neurological and developmental outcome in relation to the gestational age (GA), mode of conception and other perinatal risk factors in a group of twins. Study design: The documentation of twins referred for follow-up in the period from 1998 to 2016 was studied retrospectively. Data concerning the quality of GMs, perinatal risk factors and developmental outcome were analysed. Subjects: Eighty-nine twin pairs, GA from 24 to 38 weeks (median 35.0; IQR 3), birth weight 670 g–3820 g (median 2323; IQR 645) were included. Outcome measures: Results of neurological, psychological and speech/language development and school outcome were analysed. Results: GMs at term age and at three to four months postterm age did not differ with regard to the mode of conception. Preterm birth was significantly related to GMs at three to four months postterm age. At term age, GMs were significantly related to neurological outcome, while at three to four months postterm age, GMs were related to both the neurological and psychological outcome. Difficulties in speech/language development were diagnosed in almost half of the children, more frequently in boys and children with lower Apgar scores. Conclusion: The study highlights the value of GMs for predicting the developmental outcome in twins and indicates the importance of developmental, especially speech/language, follow-up in twins. Highlights: GMs have predictive value for neurological outcome in twins. GMs did not differ with regard to the mode of conception. There was significant correlation of all measures of outcome with small for gestational age. Mode of conception was significantly related to psychological and language outcome only.