Fimbriae and related receptors for Salmonella Enteritidis. (January 2019)

• Record Type: Journal Article
• Authors: Quan, Guomei; Xia, Pengpeng; Zhao, Jing; Zhu, Chunhong; Meng, Xia; Yang, Yuqian; Wang, Yiting; Tian, Yan; Ding, Xiuyan; Zhu, Guoqiang
• Is Part Of: Microbial pathogenesis. Volume 126(2019)
• Page Start: 357
• Page End: 362
• Publication Date: 2019-01
• Subjects: Salmonella enteritidis -- Fimbriae -- Receptor -- Immunity; Pathogenic microorganisms -- Periodicals; Pathology, Molecular -- Periodicals; Communicable Diseases -- microbiology -- Periodicals; Communicable Diseases -- parasitology -- Periodicals; Micro-organismes pathogènes -- Périodiques; Pathologie moléculaire -- Périodiques; Electronic journals; 616.9041
• DOI: 10.1016/j.micpath.2018.10.025
• Languages: English
• ISSNs: 0882-4010

Abstract

Abstract: Infection with Salmonella Enteritidis (SE) is one of the main causes for food- and water-borne diseases, and is a major concern to public health for both humans and animals worldwide. Some fimbrial antigens expressed by SE strains have been described and characterized, containing SEF14, SEF17, SEF21, long polar fimbriae and plasmid-encoded fimbriae, they play a role in bacterial survival in the host or external environment. However, their functions remain to be well elucidated, with the initial attachment and binding for fimbriae-mediated SE infections only minimally understood. Meanwhile, host-pathogen interactions provide insights into receptor modulation of the host innate immune system. Therefore, to well understand the pathogenicity of SE bacteria and to comprehend the host response to infection, the host cell-SE interactions need to be characterized. This review describes SE fimbriae receptors with an emphasis on the interaction between the receptor and SE fimbriae. Highlights: Salmonella enterica serovar enteritidis is an invasive non-typhoidal and intracellular pathogen of human and animals. Fimbriae are important virulence factors for Salmonella pathogenesis. Attachment of the bacteria to the host cell depends on cooperation between adhesin and specific receptors on the host cell.