An emerging novel virus: Atypical porcine pestivirus (APPV). (9th November 2018)

• Record Type: Journal Article
• Authors: Pan, Shuonan; Mou, Chunxiao; Chen, Zhenhai
• Is Part Of: Reviews in medical virology. Volume 29:Number 1(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-11-09
• Subjects: congenital tremor -- pestivirus -- porcine -- prevention and control; Medical virology -- Periodicals; Review Literature -- Periodicals; Virus Diseases -- Periodicals; Viruses -- Periodicals; 616.0194
• DOI: 10.1002/rmv.2018
• Languages: English
• ISSNs: 1052-9276

Abstract

Summary: Emerging porcine pestivirus diseases frequently challenge prevention and control strategies in the swine industry. Over the past decade, a few novel pestiviruses have been identified in pigs. This article focuses on the recently emerging atypical porcine pestivirus (APPV) that potentially threatens global swine herd health security. The virus was first identified in 2016, in the United States and thereafter, accumulated evidence shows that it is currently distributed in three continents. The clinical presentation of APPV‐infected pigs is characterized by congenital tremor (CT) type A‐II in piglets, while adult pigs may become persistent carriers and shedders. Here, a literature review is conducted to summarize the published findings in the virus genomic biology, transmission, epidemiology, pathogenesis, and diagnosis, which would shed light on acceleration of development of anti‐APPV strategies.