Positron emission tomography/computed tomography in the diagnosis, staging, and prognostic evaluation of natural killer/T-cell lymphoma. Issue 12 (December 2018)

• Record Type: Journal Article
• Authors: Ding, Jian-Jun; Chen, Ya-Lian; Zhou, Shui-Hong; Zhao, Kui
• Is Part Of: Journal of international medical research. Volume 46:Issue 12(2018)
• Page Start: 4920
• Page End: 4929
• Publication Date: 2018-12
• Subjects: Natural killer/T-cell lymphoma -- non-Hodgkin's lymphoma -- diagnosis -- 18F-fluorodexoyglucose-positron emission tomography/computed tomography -- prognosis -- staging; Medicine -- Periodicals; Pharmacology -- Periodicals; 610.5
• DOI: 10.1177/0300060518804375
• Languages: English
• ISSNs: 0300-0605

Abstract

Natural killer/T-cell lymphoma (NKTL) is a rare subtype of non-Hodgkin's lymphoma that is associated with Epstein–Barr virus infection. The clinicopathological features of NKTL are unique among lymphomas. NKTL is an aggressive disease with a poor prognosis in the absence of effective treatment. Accurate diagnosis and staging are essential to ensure an appropriate treatment strategy and accurate prognosis of NKTL. 18 F-Fluorodexoyglucose-positron emission tomography/computed tomography ( 18 F-FDG PET/CT) is a valuable technique in the diagnosis, staging, and prognostic evaluation of various types of malignant tumors, including NKTL. PET/CT imaging studies of patients with NKTL have shown that NKTL is 18 F-FDG-avid and that PET/CT is superior to conventional methods in detecting cutaneous and extracutaneous lesions. We herein review recent PET/CT studies that have provided considerable insight into the diagnosis, staging, prognostic evaluation, and treatment effectiveness in patients with NKTL.