Share and share alike: the role of Tra1 from the SAGA and NuA4 coactivator complexes. Issue 1 (1st January 2019)

• Record Type: Journal Article
• Authors: Cheung, Alan C. M.; Díaz-Santín, Luis Miguel
• Is Part Of: Transcription. Volume 10:Issue 1(2019)
• Page Start: 37
• Page End: 43
• Publication Date: 2019-01-01
• Subjects: Tra1 -- SAGA -- NuA4 -- histone acetylation -- coactivator -- activator; Chromatin and transcription -- Eukaryotic transcription -- Transcription factors and co-activators; Genetic transcription -- Periodicals; 572.8
• DOI: 10.1080/21541264.2018.1530936
• Languages: English
• ISSNs: 2154-1264

Abstract

ABSTRACT: SAGA and NuA4 are coactivator complexes required for transcription on chromatin. Although they contain different enzymatic and biochemical activities, both contain the large Tra1 subunit. Recent electron microscopy studies have resolved the complete structure of Tra1 and its integration in SAGA/NuA4, providing important insight into Tra1 function.