AgSbF6-Catalyzed anti-Markovnikov hydroboration of terminal alkynes. Issue 7 (4th January 2019)

• Record Type: Journal Article
• Authors: Mamidala, Ramesh; Pandey, Vipin K.; Rit, Arnab
• Is Part Of: Chemical communications. Volume 55:Issue 7(2019)
• Page Start: 989
• Page End: 992
• Publication Date: 2019-01-04
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c8cc07499b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : AgSbF6 -Catalyzed atom-economic anti -Markovnikov hydroboration of terminal alkynes which works at room temperature under solvent-free condition to produce E -vinylboronates is developed. Abstract : AgSbF6 -Catalyzed anti -Markovnikov addition of pinacolborane (HBpin) to terminal alkynes to produce the E -vinylboronates is reported. This efficient methodology is scalable, compatible with sterically and electronically diverse alkynes, and works at room temperature under solvent-free condition. The utility of this method is demonstrated in the facile synthesis of the clinically important ( E )-2, 4, 3′, 5′-tetramethoxystilbene.