Polydopamine-coated magnetic mesoporous silica nanoparticles for multimodal cancer theranostics. Issue 3 (19th December 2018)

• Record Type: Journal Article
• Authors: Shi, Menghan; Zhang, Jiulong; Li, Jingchao; Fan, Yu; Wang, Jianhong; Sun, Wenjie; Yang, Hong; Peng, Chen; Shen, Mingwu; Shi, Xiangyang
• Is Part Of: Journal of materials chemistry. Volume 7:Issue 3(2018)
• Page Start: 368
• Page End: 372
• Publication Date: 2018-12-19
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c8tb03021a
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : Polydopamine-coated mesoporous silica nanoparticles loaded with ultrasmall Fe3 O4 nanoparticles can be prepared for multimodal imaging and combination therapy of tumors. Abstract : Polydopamine-coated magnetic mesoporous silica nanoparticles have been designed by loading ultrasmall iron oxide nanoparticles within hollow mesoporous silica nanopartricles and then coating polydopamine onto the particle surface. The developed nanoplatform displayed improved colloidal stability, enhanced r 1 relaxivity and near infrared absorption feature, affording their use for multimodal cancer theranostics.