Aging‐associated perifollicular changes and calcium deposition in poodles. Issue 1 (21st November 2018)

• Record Type: Journal Article
• Authors: Miragliotta, Vincenzo; Buonamici, Sharon; Coli, Alessandra; Abramo, Francesca
• Is Part Of: Veterinary dermatology. Volume 30:Issue 1(2019)
• Page Start: 56
• Page End: e15
• Publication Date: 2018-11-21
• Subjects: Veterinary dermatology -- Periodicals; Pet medicine -- Periodicals; 636.08965
• DOI: 10.1111/vde.12700
• Languages: English
• ISSNs: 0959-4493

Abstract

Abstract : Background: It is commonly accepted that canine dystrophic mineralization of the hair follicle glassy membrane can be seen in hyperadrenocorticism and as a senile change in poodles. Pathology textbooks define this change as deposition of calcium salts in the form of basophilic, amorphous, granular material along collagen fibrils. Hypothesis/Objectives: The aim was to evaluate whether the incidence of the lesion is specific to poodles and if it is always associated with calcium deposition. Animals: One hundred and forty‐seven dogs divided into three groups: (i) 91 normal poodles; (ii) 40 dogs of other breeds; and (iii) 16 dogs with clinical/histopathological diagnosis of hyperadrenocorticism. Methods and materials: Retrospective study; with haematoxylin and eosin, and von Kossa staining. Results: Our findings demonstrate that perifollicular changes of the hair follicle glassy membrane of poodles are not always associated with calcium deposition. Conclusions and clinical importance: A specific staining is needed to identify true calcium deposition when performing histological examination of the skin of poodles. Abstract : Background – It is commonly accepted that canine dystrophic mineralization of the hair follicle glassy membrane can be seen in hyperadrenocorticism and as a senile change in poodles. Pathology textbooks define this change as deposition of calcium salts in the form of basophilic, amorphous, granular material along collagen fibrils.Hypothesis/Objectives – The aim was to evaluate whether the incidence of the lesion is specific to poodles and if it is always associated with calcium deposition.Conclusions and clinical importance – A specific staining is needed to identify true calcium deposition when performing histological examination of the skin of poodles.