A retrospective analysis of re‐exploration after living donor right lobe liver transplantation: incidence, causes, outcomes, and risk factors. (2nd October 2018)

• Record Type: Journal Article
• Authors: Park, Jungchan; Choi, Gyu‐Seong; Gwak, Mi Sook; Ko, Justin Sangwook; Han, Bobae; Han, Sangbin; Joh, Jae Won; Lee, Suk‐Koo; Kim, Jongman; Kim, Gaab Soo
• Is Part Of: Transplant international. Volume 32:Number 2(2019)
• Page Start: 141
• Page End: 152
• Publication Date: 2018-10-02
• Subjects: incidence -- living donor right lobe liver transplantation -- outcome -- re‐exploration; Transplantation of organs, tissues, etc -- Periodicals; 617.95405
• DOI: 10.1111/tri.13335
• Languages: English
• ISSNs: 0934-0874

Abstract

Summary: Despite technical difficulties, right lobe liver grafting is preferred in living donor liver transplantation because of the graft size. Re‐exploration after living donor right lobe liver transplantation (LRLT) has never been separately analyzed. We aimed to analyze the incidence, causes, outcomes, and risk factors of re‐exploration after LRLT. We reviewed medical records of 1016 LRLT recipients from October 2003 to July 2017 and identified recipients who underwent re‐exploration within hospital stay. Separate analyses were also performed according to cause of re‐exploration. The overall incidence of re‐exploration was 17.0% (173/1016). The most common cause of re‐exploration was bleeding (50%). Overall re‐exploration was associated with clinical outcome, but different results were shown on analyses according to cause of re‐exploration. Risk factors of re‐exploration were underlying hepatocellular carcinoma and operative duration [Odds ratio (OR), 1.49; 95% confidence interval (CI), 1.05–2.12; P = 0.03, and OR, 1.002; 95% CI, 1.001–1.004; P = 0.0023, respectively]. Re‐exploration after LRLT is relatively common, and is strongly associated with mortality and graft failure.