Adolescence and risk of preterm birth in multifetal gestations. (18th April 2019)

• Record Type: Journal Article
• Authors: Alrahmani, Layan; Abdelsattar, Zaid M.; Adekola, Henry; Gonik, Bernard; Awonuga, Awoniyi
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 32:Number 8(2019)
• Page Start: 1321
• Page End: 1324
• Publication Date: 2019-04-18
• Subjects: Adolescents -- multiple gestations -- prematurity -- twins; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.1080/14767058.2017.1404981
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: Objective: The objective of this study is to evaluate if adolescence confers additional risk for preterm delivery in multifetal gestations. Methods: This is a retrospective review of all twin and triplet deliveries from 8/2008 to 12/2012 at two Detroit Hospitals. Outcomes in adolescent mothers aged 19 or younger ( n = 59) were compared with adult controls aged 20–34 ( n = 350). Results: Mean gestational age at delivery in adolescents was 31.3 (SD: 5.8) weeks versus 34.2 (SD: 4.3) weeks in adults ( p < .001). On multivariable analysis, adolescence was associated with preterm delivery (adjusted odds ratio [aOR], 2.3; 95% confidence intervals [95% CI], 1.1–4.7, p = .02) and early-preterm delivery (aOR, 2.2; 95% CI 1.2–4; p = .01). Adjusted rates of preterm and early-preterm delivery were markedly higher in adolescents compared with controls. Being an adolescent was also a significant risk factor for iatrogenic preterm delivery (aOR, 2.4; 95% CI 1.1–5.5; p = .04). Conclusions: Adolescents pregnant with twins or triplets deliver 3 weeks, on average, before adults and are at markedly increased risk of preterm and early-preterm delivery.