Micellar promoted multi-component synthesis of 1, 2, 3-triazoles in water at room temperature. Issue 3 (26th January 2015)

• Record Type: Journal Article
• Authors: Tasca, Elena; La Sorella, Giorgio; Sperni, Laura; Strukul, Giorgio; Scarso, Alessandro
• Is Part Of: Green chemistry. Volume 17:Issue 3(2015)
• Page Start: 1414
• Page End: 1422
• Publication Date: 2015-01-26
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/c4gc02248c
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : Micellar media in water provide a simple and efficient environment favoring the multi-component synthesis of 1, 2, 3-triazoles from organic bromides, sodium azide and terminal alkynes in the presence of [Cu(IMes)Cl]1 catalyst at room temperature within a few hours. Abstract : Micellar media in water provide a simple and efficient environment favoring the multi-component synthesis of 1, 2, 3-triazoles from organic bromides, sodium azide and terminal alkynes in the presence of [Cu(IMes)Cl]1 catalyst at room temperature within a few hours. The micellar medium favors both the in situ formation of the organic azide and its metal promoted cycloaddition with the alkyne.