Heteroatom-substituted tetra(3, 4-pyrido)porphyrazines: a stride toward near-infrared-absorbing macrocycles. Issue 20 (17th April 2015)

• Record Type: Journal Article
• Authors: Vachova, Lenka; Machacek, Miloslav; Kučera, Radim; Demuth, Jiri; Cermak, Pavel; Kopecky, Kamil; Miletin, Miroslav; Jedlickova, Adela; Simunek, Tomas; Novakova, Veronika; Zimcik, Petr
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 20(2015)
• Page Start: 5608
• Page End: 5612
• Publication Date: 2015-04-17
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00651a
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : Synthesis and photophysical properties are reported for substituted tetra(3, 4-pyrido)porphyrazines that absorb light as far as at 800 nm. Abstract : A synthesis procedure for heteroatom-substituted tetra(3, 4-pyrido)porphyrazines that absorb light near 800 nm was developed. Based on the observed relationships between the structure and photophysical parameters, a novel highly photodynamically active (IC50 = 0.26 μM) compound was synthesized and biologically characterized.