Positive reactions to gold sodium thiosulfate in patch test panels (TRUE Test) in Japan: A multicentre study. (10th September 2018)

• Record Type: Journal Article
• Authors: Suzuki, Kayoko; Yagami, Akiko; Ito, Akiko; Kato, Atsuko; Miyazawa, Hitoshi; Kanto, Hiromi; Matsunaga, Kayoko
• Is Part Of: Contact dermatitis. Volume 80:Number 2(2019)
• Page Start: 114
• Page End: 117
• Publication Date: 2018-09-10
• Subjects: active sensitization -- gold sodium thiosulfate -- late reaction -- patch test; Contact dermatitis -- Periodicals; 616.51
• DOI: 10.1111/cod.13105
• Languages: English
• ISSNs: 0105-1873

Abstract

Abstract : Background: The proportion of positive test results with gold sodium thiosulfate included in a patch test panel (P‐GST) had been found to be greater than that with gold sodium thiosulfate 0.5% pet. by allergEAZE (A‐GST). Objectives: To compare positive reactions to P‐GST and A‐GST, and to evaluate late reactions after the day (D) 7 reading. Methods: A retrospective analysis was performed of 588 patients at participating departments (119 males; 469 females) who were patch tested with P‐GST and A‐GST in May 2015 to March 2016. Results: Positive test reactions to P‐GST and A‐GST were observed in 15% and 6% of patients, respectively. Three patients reported a positive reaction occurring after the D7 reading. Conclusions: Gold sodium thiosulfate often gives a positive reaction after 2 to 3 weeks, and, in such cases, the positive reaction may be sustained, so it is recommended to assess the reaction for up to 1 month after application.