Sinus floor elevation in sites with a perforated schneiderian membrane: What is the effect of placing a collagen membrane in a rabbit model?. Issue 12 (27th December 2018)

• Record Type: Journal Article
• Authors: Lim, Hyun‐Chang; Son, Yeojin; Hong, Ji‐Youn; Shin, Seung‐Il; Jung, Ui‐Won; Chung, Jong‐Hyuk
• Is Part Of: Clinical oral implants research. Volume 29:Issue 12(2018)
• Page Start: 1202
• Page End: 1211
• Publication Date: 2018-12-27
• Subjects: animal study -- collagen membrane -- perforation -- schneiderian membrane -- sinus floor elevation; Dental implants -- Research -- Periodicals; 617.69
• DOI: 10.1111/clr.13385
• Languages: English
• ISSNs: 0905-7161

Abstract

Abstract: Objective: To investigate the healing following sinus grafting in sites with a perforated schneiderian membrane repaired using a collagen membrane, compared to control sites without membrane perforation. Materials & Methods: Following elevation of the sinus membrane in 16 rabbits, each sinus was assigned to one of the following groups: (a) intentional schneiderian membrane perforation, followed by the placement of a collagen membrane and bone grafting (group SMP) and (b) bone grafting without a perforation of the schneiderian membrane and without a collagen membrane placement (control group). At 2 and 4 weeks ( n = 8 for each time‐point), microcomputed tomographic (micro‐CT) and histomorphometric analyses were performed. Results: Overall new bone formation in group SMP was significantly delayed compared to the control group at 2 and 4 weeks (1.58 ± 1.25% vs. 9.23 ± 2.69% at 2 weeks, 10.43 ± 3.55 vs. 17.86 ± 4.11% at 4 weeks, p < 0.05). At 2 weeks, new bone formation for the areas close to lateral (1.19 ± 2.02%) and medial sinus bone walls (3.17 ± 1.98%) was markedly delayed in group SMP compared to the control group (13.08 ± 6.13% and 12.75 ± 5.63%, respectively, p < 0.05), but there was no statistical difference in those areas at 4 weeks ( p > 0.05). The augmented volumes at 2 and 4 weeks were not statistically significantly different in both groups. Conclusion: The perforation of the schneiderian membrane and the repair using a collagen membrane delayed new bone formation in the augmented sinuses. However, the extension of the collagen membrane on the sinus bone walls was also attributable to this delayed bone formation.