Multivalency in Rab effector interactions. (2nd January 2019)

• Record Type: Journal Article
• Authors: Rai, Amrita; Goody, Roger S.; Müller, Matthias P.
• Is Part Of: Small GTPases. Volume 10:Number 1(2019)
• Page Start: 40
• Page End: 46
• Publication Date: 2019-01-02
• Subjects: bMERB -- EHBPs -- Gcc185 -- Micals -- multivalency -- MyoV -- Rab effectors -- Rabenosyn-5; Guanosine triphosphatase -- Periodicals; Guanosine triphosphatase; Periodicals; 572.793
• DOI: 10.1080/21541248.2016.1265700
• Languages: English
• ISSNs: 2154-1256

Abstract

ABSTRACT: Rab proteins regulate vesicular transport in eukaryotic cells and establish connections to various cellular structures and processes by interacting with so-called effector molecules. Several of these effectors are known to not only bind a single Rab protein, but to be able to bind multiple different Rabs simultaneously. In this review we will give a short overview of effectors in general and (putative) functions of the aforementioned multivalent Rab:effector interactions.