DIY 3D Microparticle Generation from Next Generation Optofluidic Fabrication. Issue 7 (1st June 2018)

• Record Type: Journal Article
• Authors: Paulsen, Kevin S.; Deng, Yanxiang; Chung, Aram J.
• Is Part Of: Advanced science. Volume 5:Issue 7(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-06-01
• Subjects: 3D microparticles -- inertial microfluidics -- optofluidic fabrication -- optofluidics; Science -- Periodicals; 505
• DOI: 10.1002/advs.201800252
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract: Complex‐shaped microparticles can enhance applications in drug delivery, tissue engineering, and structural materials, although techniques to fabricate these particles remain limited. A microfluidics‐based process called optofluidic fabrication that utilizes inertial flows and ultraviolet polymerization has shown great potential for creating highly 3D‐shaped particles in a high‐throughput manner, but the particle dimensions are mainly at the millimeter scale. Here, a next generation optofluidic fabrication process is presented that utilizes on‐the‐fly fabricated multiscale fluidic channels producing customized sub‐100 µm 3D‐shaped microparticles. This flexible design scheme offers a user‐friendly platform for rapid prototyping of new 3D particle shapes, providing greater potential for creating impactful engineered microparticles. Abstract : A next generation optofluidic fabrication process is presented that utilizes on‐the‐fly fabricated multiscale fluidic channels producing customized sub‐100 µm 3D‐shaped microparticles. This flexible design scheme offers a user‐friendly platform for rapid prototyping of new 3D particle shapes, providing greater potential for creating impactful engineered microparticles.