Isoprenylated phenolic compounds with tyrosinase inhibition from Morus nigra. Issue 5 (4th May 2018)

• Record Type: Journal Article
• Authors: Hu, Xiao; Yu, Mei-Hua; Yan, Gui-Rui; Wang, He-Yao; Hou, Ai-Jun; Lei, Chun
• Is Part Of: Journal of Asian natural products research. Volume 20:Issue 5(2018)
• Page Start: 488
• Page End: 493
• Publication Date: 2018-05-04
• Subjects: Morus nigra -- Moraceae -- isoprenylated phenolic compounds -- nigrasin K -- mushroom tyrosinase; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2017.1350653
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: A new isoprenylated sanggenon-type flavanone, nigrasin K (1 ), together with three known analogs (2 –4 ) and five known Diels–Alder adducts (5 –9 ), were isolated from the twigs of Morus nigra . Their structures were elucidated by spectroscopic methods. Sanggenon M (2 ), chalcomoracin (5 ), sorocein H (6 ), kuwanon J (7 ), sanggenon C (8 ), and sanggenon O (9 ) showed significant inhibitory effects on mushroom tyrosinase. Abstract :