Knee extension strength and post-operative functional prediction in quadriceps resection for soft-tissue sarcoma of the thigh. Issue 6 (June 2016)

• Record Type: Journal Article
• Authors: Tanaka, A.; Yoshimura, Y.; Aoki, K.; Kito, M.; Okamoto, M.; Suzuki, S.; Momose, T.; Kato, H.
• Is Part Of: Bone & joint research. Volume 5:Issue 6(2016)
• Page Start: 232
• Page End: 238
• Publication Date: 2016-06
• Subjects: Soft-tissue sarcoma -- Quadriceps muscle -- Muscle strength -- Post-operative function -- Prediction; Musculoskeletal system -- Periodicals; 573.705
• DOI: 10.1302/2046-3758.56.2000631
• Languages: English
• ISSNs: 2046-3758

Abstract

Abstract : Objectives: Our objective was to predict the knee extension strength and post-operative function in quadriceps resection for soft-tissue sarcoma of the thigh. Methods: A total of 18 patients (14 men, four women) underwent total or partial quadriceps resection for soft-tissue sarcoma of the thigh between 2002 and 2014. The number of resected quadriceps was surveyed, knee extension strength was measured with the Biodex isokinetic dynamometer system (affected side/unaffected side) and relationships between these were examined. The Musculoskeletal Tumor Society (MSTS) score, Toronto Extremity Salvage Score (TESS), European Quality of Life-5 Dimensions (EQ-5D) score and the Short Form 8 were used to evaluate post-operative function and examine correlations with extension strength. The cutoff value for extension strength to expect good post-operative function was also calculated using a receiver operating characteristic (ROC) curve and Fisher's exact test. Results: Extension strength decreased when the number of resected quadriceps increased (p < 0.001), and was associated with lower MSTS score, TESS and EQ-5D (p = 0.004, p = 0.005, p = 0.006, respectively). Based on the functional evaluation scales, the cutoff value of extension strength was 56.2%, the equivalent to muscle strength with resection of up to two muscles. Conclusion: Good post-operative results can be expected if at least two quadriceps muscles are preserved. Cite this article: A. Tanaka, Y. Yoshimura, K. Aoki, M. Kito, M. Okamoto, S. Suzuki, T. Momose, H. Kato. Knee extension strength and post-operative functional prediction in quadriceps resection for soft-tissue sarcoma of the thigh. Bone Joint Res 2016;5:232–238. DOI: 10.1302/2046-3758.56.2000631.