Cover Feature: Mannose‐Decorated Multicomponent Supramolecular Polymers Trigger Effective Uptake into Antigen‐Presenting Cells (ChemBioChem 9/2018). (19th April 2018)

• Record Type: Journal Article
• Authors: Straßburger, David; Stergiou, Natascha; Urschbach, Moritz; Yurugi, Hajime; Spitzer, Daniel; Schollmeyer, Dieter; Schmitt, Edgar; Besenius, Pol
• Is Part Of: Chembiochem. Volume 19:Number 9(2018)
• Page Start: 894
• Page End: 894
• Publication Date: 2018-04-19
• Subjects: amphiphiles -- peptides -- polymers -- self-assembly -- supramolecular chemistry; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1002/cbic.201800191
• Languages: English
• ISSNs: 1439-4227

Abstract

Abstract : The cover feature picture shows the supramolecular copolymerisation of a dendritic peptide amphiphile monomer bearing mannosides and a second monomer carrying tetra(ethylene glycol)s and labelled with a Cy3 fluorescent probe. The multicomponent mannose‐decorated copolymers trigger the uptake into macrophages as antigen‐presenting cells that play a key role in the innate immune response. More information can be found in the communication by E. Schmitt, P. Besenius et al. onpage 912 in Issue 9, 2018 (DOI:10.1002/cbic.201800114 )