High‐resolution fiber‐optic dosimeters for microbeam radiation therapy. Issue 5 (17th April 2017)

• Record Type: Journal Article
• Authors: Archer, James; Li, Enbang; Petasecca, Marco; Lerch, Michael; Rosenfeld, Anatoly; Carolan, Martin
• Is Part Of: Medical physics. Volume 44:Issue 5(2017)
• Page Start: 1965
• Page End: 1968
• Publication Date: 2017-04-17
• Subjects: fiber‐optic dosimetry -- microbeam radiation therapy -- scintillators -- x‐ray; Medical physics -- Periodicals; Medical physics; Geneeskunde; Natuurkunde; Toepassingen; Biophysics; Periodicals; Periodicals; Electronic journals; 610.153
• DOI: 10.1002/mp.12209
• Languages: English
• ISSNs: 0094-2405

Abstract

Abstract : Purpose: A high resolution, water equivalent, optical and passive x‐ray dosimeter has been constructed using plastic scintillator and optical fiber. This dosimeter has a peak edge‐on spatial resolution of 100 μm in one dimension, with a 10 μm resolution dosimeter under investigation. The dosimeter design has a potential application in synchrotron x‐ray microbeam radiation therapy where a high resolution is vital for accurate dose measurements and quality assurance. Methods: BC‐400 plastic scintillator, of thickness 100 μm, was optically coupled to an optical fiber with core diameter 1 mm. The end was coated in optical paint to improve sensitivity. An identical fiber was made without the scintillator to measure the background Cherenkov radiation induced in the fiber, to allow background signal subtraction. The light captured by the fibers was measured by PMTs. The probe system was exposed to a 6 MV, 10 × 10 cm 2 LINAC x‐ray field and the beam profile was measured at 100 cm, as well as the depth dose profile. Results: The measured profiles matched well with ionisation chamber data. Important beam parameters such as penumbra width and percent depth dose at various depths matched the ionisation chamber data, within uncertainty. Conclusions: This work demonstrates that high resolutions can be achieved with a scintillation and optical fiber system. The probe is water‐equivalent, passive, energy independent, radiation hard and inexpensive, making it ideal for further improvements for use with microbeam radiation therapy.