HIV‐Positive‐to‐HIV‐Positive Liver Transplantation. Issue 8 (7th June 2016)

• Record Type: Journal Article
• Authors: Calmy, A.; van Delden, C.; Giostra, E.; Junet, C.; Rubbia Brandt, L.; Yerly, S.; Chave, J.‐P.; Samer, C.; Elkrief, L.; Vionnet, J.; Berney, T.
• Other Names: Aubert V. investigator.; Battegay M. investigator.; Bernasconi E. investigator.; Böni J. investigator.; Bucher H.C. investigator.; Cavassini M. investigator.; Dollenmaier G. investigator.; Egger M. investigator.; Elzi L. investigator.; Fehr J. investigator.; Fellay J. investigator.; Furrer H. investigator.; Fux C.A. investigator.; Gorgievski M. investigator.; Günthard H. investigator.; Haerry D. investigator.; Hasse B. investigator.; Hirsch H.H. investigator.; Hoffmann M. investigator.; Hösli I. investigator.; Kahlert C. investigator.; Kaiser L. investigator.; Keiser O. investigator.; Klimkait T. investigator.; Kouyos R. investigator.; Kovari H. investigator.; Ledergerber B. investigator.; Martinetti G. investigator.; Martinez de Tejada B. investigator.; Metzner K. investigator.; Müller N. investigator.; Nadal D. investigator.; Nicca D. investigator.; Pantaleo G. investigator.; Rauch A. investigator.; Regenass S. investigator.; Rickenbach M. investigator.; Rudin C. investigator.; Schöni‐Affolter F. investigator.; Schmid P. investigator.; Schüpbach J. investigator.; Speck R. investigator.; Tarr P. investigator.; Telenti A. investigator.; Trkola A. investigator.; Vernazza P. investigator.; Weber R. investigator.; Achermann R. investigator.; Amico P. investigator.; Aubert J.‐D. investigator.; Baumann P. investigator.; Beldi G. investigator.; Benden C. investigator.; Berger C. investigator.; Binet I. investigator.; Bochud P.‐Y. investigator.; Boely E. investigator.; Bucher H. investigator.; Bühler L. investigator.; Carell T. investigator.; Catana E. investigator.; Chalandon Y. investigator.; de Geest S. investigator.; de Rougemont O. investigator.; Dickenmann M. investigator.; Duchosal M. investigator.; Fehr T. investigator.; Ferrari‐Lacraz S. investigator.; Garzoni C. investigator.; Gasche Soccal P. investigator.; Golshayan D. investigator.; Good D. investigator.; Hadaya K. investigator.; Halter J. investigator.; Heim D. investigator.; Hess C. investigator.; Hillinger S. investigator.; Hirsch H.H. investigator.; Hofbauer G. investigator.; Huynh‐Do U. investigator.; Immer F. investigator.; Klaghofer R. investigator.; Koller M. investigator.; Laesser B. investigator.; Lehmann R. investigator.; Lovis C. investigator.; Manuel O. investigator.; Marti H.‐P. investigator.; Martin P.Y. investigator.; Martinolli L. investigator.; Meylan P. investigator.; Mohacsi P. investigator.; Morard I. investigator.; Morel P. investigator.; Mueller U. investigator.; Mueller N.J. investigator.; Mueller‐McKenna H. investigator.; Müller A. investigator.; Müller T. investigator.; Müllhaupt B. investigator.; Nadal D. investigator.; Pascual M. investigator.; Passweg J. investigator.; Piot Ziegler C. investigator.; Rick J. investigator.; Roosnek E. investigator.; Rosselet A. investigator.; Rothlin S. investigator.; Ruschitzka F. investigator.; Schanz U. investigator.; Schaub S. investigator.; Seiler C. investigator.; Stampf S. investigator.; Steiger J. investigator.; Stirnimann G. investigator.; Toso C. investigator.; Tsinalis D. investigator.; Venetz J.‐P. investigator.; Villard J. investigator.; Wick M. investigator.; Wilhelm M. investigator.;
• Is Part Of: American journal of transplantation. Volume 16:Issue 8(2016:Aug.)
• Page Start: 2473
• Page End: 2478
• Publication Date: 2016-06-07
• Subjects: clinical research/practice -- ethics and public policy -- infectious disease -- immune deficiency -- patient safety; Transplantation of organs, tissues, etc -- Periodicals; 617.95
• DOI: 10.1111/ajt.13824
• Languages: English
• ISSNs: 1600-6135

Abstract

Abstract : Most countries exclude human immunodeficiency virus (HIV)‐positive patients from organ donation because of concerns regarding donor‐derived HIV transmission. The Swiss Federal Act on Transplantation has allowed organ transplantation between HIV‐positive donors and recipients since 2007. We report the successful liver transplantation from an HIV‐positive donor to an HIV‐positive recipient. Both donor and recipient had been treated for many years with antiretroviral therapy and harbored multidrug‐resistant viruses. Five months after transplantation, HIV viremia remains undetectable. This observation supports the inclusion of appropriate HIV‐positive donors for transplants specifically allocated to HIV‐positive recipients. Abstract : The authors report the first liver transplant from an HIV‐positive donor to an HIV‐positive recipient with a successful outcome at 6 months, and argue that the medical and social advances represented by this case call for legal and political progress. See the editorial from Fishman and Feng onpage 2252 .