DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program. Issue 9 (11 September 0207)

• Record Type: Journal Article
• Authors: Djoussé, Luc; Ho, Yuk‐Lam; Nguyen, Xuan‐Mai T.; Gagnon, David R.; Wilson, Peter W.F.; Cho, Kelly; Gaziano, J. Michael
• Other Names: Halasz Ildiko investigator.; Federman Daniel investigator.; Beckham Jean investigator.; Sherman Scott E. investigator.; Sriram Peruvemba investigator.; Tsao Philip S. investigator.; Boyko Edward J. investigator.; Xu Junzhe investigator.; Lederle Frank investigator.; Dellitalia Louis J. investigator.; McArdle Rachel investigator.; Kaminsky Laurence investigator.; Swann Alan C. investigator.; Hamner Mark B. investigator.; Florez Hermes J. investigator.; Pandya Prashant investigator.; Villarreal Gerardo investigator.; Wilson Peter investigator.; Morgan Timothy R. investigator.; Davis Lori investigator.; Hurley Robin A. investigator.; Meyer Laurence investigator.; Ahuja Sunil K. investigator.; Konicki Eric P. investigator.; Cohen David investigator.; Lichy Jack investigator.; Whittle Jeffrey investigator.; Haddock Kathlyn Sue investigator.; Straub Karl D. investigator.; Callaghan John T. investigator.; Aguayo Samuel M. investigator.; Gupta Samir investigator.; Washburn Ronald G. investigator.; Oehlert Mary E. investigator.; Hung Adriana M. investigator.; Wallbom Agnes investigator.; Keith Robert investigator.; Sonel Elif investigator.; Schifman Ronald B. investigator.; Childress Richard D. investigator.; Godschalk Michael F. investigator.; Shuldiner Alan R. investigator.; Rastogi Padmashri investigator.; Gutierrez Salvador investigator.; Fernando Ronald investigator.; Iruvanti Pran R. investigator.; Jhala Darshana investigator.; Rosado‐Rodriguez Carlos investigator.; Mastorides Stephen M. investigator.; Harley John B. investigator.; Mattocks Kristin investigator.; Striker Robert T. investigator.; Rauchman Michael investigator.; Wells John investigator.; Ballas Zuhair K. investigator.; Woods Susan S. investigator.; Yeh Shing investigator.; Ratcliffe Nora R. investigator.; Klein Jon B. investigator.; Golden Adam G. investigator.; Ginzburg Harold M. investigator.; Sharma Satish investigator.; Oursler Kris Ann K. investigator.; Whooley Mary A. investigator.; Gibson Gretchen investigator.;
• Is Part Of: Journal of the American Heart Association. Volume 7:Issue 9(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 0207-09-11
• Subjects: coronary artery disease -- epidemiology -- nutrition; Heart -- Diseases -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; Cerebrovascular disease -- Periodicals; Cardiology -- Periodicals; 616.1
• DOI: 10.1161/JAHA.117.008089
• Languages: English
• ISSNs: 2047-9980

Abstract

Abstract : Background: While adherence to healthful dietary patterns has been associated with a lower risk of coronary artery disease (CAD) in the general population, limited data are available among US veterans. We tested the hypothesis that adherence to Dietary Approach to Stop Hypertension (DASH) food pattern is associated with a lower risk of developing CAD among veterans. Methods and Results: We analyzed data on 153 802 participants of the Million Veteran Program enrolled between 2011 and 2016. Information on dietary habits was obtained using a food frequency questionnaire at enrollment. We used electronic health records to assess the development of CAD during follow‐up. Of the 153 802 veterans who provided information on diet and were free of CAD at baseline, the mean age was 64.0 (SD=11.8) years and 90.4% were men. During a mean follow‐up of 2.8 years, 5451 CAD cases occurred. The crude incidence rate of CAD was 14.0, 13.1, 12.6, 12.3, and 11.1 cases per 1000 person‐years across consecutive quintiles of Dietary Approach to Stop Hypertension score. Hazard ratios (95% confidence interval) for CAD were 1.0 (ref), 0.91 (0.84–0.99), 0.87 (0.80–0.95), 0.86 (0.79–0.94), and 0.80 (0.73–0.87) from the lowest to highest quintile of Dietary Approach to Stop Hypertension score controlling for age, sex, body mass index, race, smoking, exercise, alcohol intake, and statin use ( P linear trend, <0.0001). Conclusions: Our data are consistent with an inverse association between Dietary Approach to Stop Hypertension diet score and incidence of CAD among US veterans.