Role of Vitamin D in Inflammatory Bowel Disease. (21st October 2016)

• Record Type: Journal Article
• Authors: Limketkai, Berkeley N.; Mullin, Gerard E.; Limsui, David; Parian, Alyssa M.
• Is Part Of: Nutrition in clinical practice. Volume 32:Number 3(2017:Jun.)
• Page Start: 337
• Page End: 345
• Publication Date: 2016-10-21
• Subjects: cholecalciferol -- Crohn's disease -- ergocalciferol -- inflammatory bowel diseases -- ulcerative colitis -- vitamin D -- vitamin D deficiency; Nutrition -- Periodicals; Diet therapy -- Periodicals; Artificial feeding -- Periodicals; 615.854
• DOI: 10.1177/0884533616674492
• Languages: English
• ISSNs: 0884-5336

Abstract

Abstract : Vitamin D is a secosteroid hormone that possesses immunomodulatory properties and has been demonstrated to potentially influence inflammatory bowel disease (IBD) pathogenesis and activity. Epidemiologic data have associated vitamin D deficiency with an increased risk of IBD, hospitalizations, surgery, and loss of response to biologic therapy. Conversely, IBD itself can lead to vitamin D deficiency. This bidirectional relationship between vitamin D and IBD suggests the need for monitoring and repletion of vitamin D, as needed, in the IBD patient. This review discusses the role of vitamin D in IBD and provides practical guidance on vitamin D repletion.