Granular cell tumor of the breast mimicking malignancy: a case report with a literature review. (December 2018)

• Record Type: Journal Article
• Authors: Fujiwara, Keishi; Maeda, Ichiro; Mimura, Hidefumi
• Is Part Of: Acta radiologica open. Volume 7:Number 12(2018)
• Publication Date: 2018-12
• Subjects: Granular cell tumors -- mammography -- ultrasound -- PAS -- S-100; Radiology -- Periodicals; Diagnostic Imaging -- Periodicals; Radiology; Periodicals; 616.075705
• DOI: 10.1177/2058460118816537
• Languages: English
• ISSNs: 2058-4601

Abstract

Granular cell tumor (GCT) is a rare neoplasm of the soft tissues and <1% of all GCTs are malignant. Initially, GCT was considered a myogenic lesion affecting the female breast (myoblastoma). We report the case of an 83-year-old woman with a palpable lump in the left breast; mammography and ultrasound showed an irregular lesion. It was difficult to differentiate it from a malignant lesion; therefore, we performed core needle biopsy and histopathologic examination and immunohistochemical studies revealed a GCT of the breast.