An anatomically realistic and adaptable prostate phantom for laser thermotherapy treatment planning. Issue 2 (24th January 2013)

• Record Type: Journal Article
• Authors: Betrouni, N.; Nevoux, P.; Leroux, B.; Colin, P.; Puech, P.; Mordon, S.
• Is Part Of: Medical physics. Volume 40:Issue 2(2013)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2013-01-24
• Subjects: Therapeutic applications -- Simulation -- Ultrasonographic imaging -- Biomedical imaging -- Magnetic resonance imaging -- Cancer; biological tissues -- biomedical MRI -- biomedical ultrasonics -- biothermics -- cancer -- laser applications in medicine -- phantoms -- radiation therapy; prostate cancer -- focal therapies -- phantom -- simulation; Involving electronic [emr] or nuclear [nmr] magnetic resonance, e.g. magnetic resonance imaging -- Diagnosis using ultrasonic, sonic or infrasonic waves -- Radiation therapy; Medical imaging -- Ultrasonography -- Cancer -- Gels -- Medical magnetic resonance imaging -- Magnetic resonance -- Anatomy -- Optical properties -- Biomedical modeling -- Medical treatment planning; Medical physics -- Periodicals; Medical physics; Geneeskunde; Natuurkunde; Toepassingen; Biophysics; Periodicals; Periodicals; Electronic journals; 610.153
• DOI: 10.1118/1.4788673
• Languages: English
• ISSNs: 0094-2405

Abstract

Abstract : Purpose: : To construct a phantom for prostate cancer laser based thermotherapy treatment planning and simulation. Methods: : A realistic and adaptable prostate phantom was designed. It exhibits the following properties: valid and complete description of the prostate anatomy, material with similar optical properties of prostate tissues and compatibility with clinical imaging protocols mainly multiparametric magnetic resonance (MR) and transrectal ultrasound imaging (TRUS). Results: : Preliminary experiments with the phantom using an interstitial laser treatment protocol allowed obtaining results similar to those obtained on preclinical model. Conclusions: : These results proved that this phantom could allow a real simulation of laser therapy procedure: target definition and fibers' placement optimization using MR imaging, treatment delivery, and finally treatment monitoring using TRUS imaging.