Modulation of Excess Electron Transfer through LUMO Gradients in DNA Containing Phenanthrenyl Base Surrogates. Issue 9 (20th January 2017)

• Record Type: Journal Article
• Authors: Roethlisberger, Pascal; Kaliginediand, Veerabhadrarao; Leumann, Christian J.
• Is Part Of: Chemistry. Volume 23:Issue 9(2017)
• Page Start: 2022
• Page End: 2025
• Publication Date: 2017-01-20
• Subjects: electron transfer -- oligonucleotides -- phenanthrene -- stacking interactions; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201605846
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: The modulation of excess electron transfer (EET) within DNA containing a dimethylaminopyrene ( C ‐AP) as an electron donor and 5‐bromouracil ( Br dU) as an electron acceptor through phenanthrenyl pairs (phen‐R) could be achieved by modifying the phenanthrenyl base surrogates with electron withdrawing and donating groups. Arranging the phenanthrenyl units to form a descending LUMO gradient increased the EET efficiency compared to the electron transfer through uniform LUMOs or an ascending LUMO gradient. Abstract : Excess electron transfer (EET) can be modulated within DNA by introducing a dimethylaminopyrene ( C ‐AP) base surrogate as an electron donor, 5‐bromouracil ( Br dU) as an electron acceptor, and by changing the electronic nature of the phenanthrenyl pair.