A nutraceutical diet based on Lespedeza spp., Vaccinium macrocarpon and Taraxacum officinale improves spontaneous feline chronic kidney disease. Issue 12 (14th June 2018)

• Record Type: Journal Article
• Authors: Di Cerbo, Alessandro; Iannitti, Tommaso; Guidetti, Gianandrea; Centenaro, Sara; Canello, Sergio; Cocco, Raffaella
• Is Part Of: Physiological reports. Volume 6:Issue 12(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-06-14
• Subjects: Aspartate aminotransferase -- blood urea nitrogen -- cat -- chronic kidney disease -- creatinine -- feline -- total proteins -- urine color score -- urine turbidity score; Physiology -- Periodicals; 571
• DOI: 10.14814/phy2.13737
• Languages: English
• ISSNs: 2051-817X

Abstract

Abstract: Chronic kidney disease is characterized by structural and/or functional impairment of one or both kidneys persisting for more than 3 months. In cats, chronic kidney disease can frequently occur in animals aged over 9 years with an incidence of approximately 10%. Thirty‐four client‐owned, neutered cats, suffering from stage II‐III chronic kidney disease and diagnosed according to the International Renal Interest Society guidelines were randomly assigned to receive either a control diet ( n = 17) or a nutraceutical diet (ND; n = 17) for 90 days. Both diets were commercialized for management of CKD symptoms. The diets were identical except that the ND contained tablets that consisted of 60–80% hydrolysed proteins, 20–40% minerals and active substances, that are, Lespedeza spp. 0.0588%, Vaccinium macrocarpom 0.0371%, and Taraxacum officinale 0.0231%. No adverse effects were reported during this study. Both diets resulted in an improvement in CKD symptoms. After a 90‐day evaluation, creatinine, blood urea nitrogen, total proteins, and aspartate aminotransferase significantly decreased in cats that received the ND. A significant decrease was also observed in urine turbidity score, color score, and total proteins in cats that received the ND. We have found that a ND based on Lespedeza spp ., Vaccinium macrocarpon, and Taraxacum officinale improves key indicators of renal failure in cats affected by chronic kidney disease. Abstract : In cats, chronic kidney disease can frequently occur in animals aged over 9 years with an incidence of approximately 10%. In this study, 34 client‐owned, neutered cats, suffering from stage II–III chronic kidney disease were randomly assigned to receive either a control diet or a nutraceutical diet for 90 days. The nutraceutical diet improved key indicators of renal failure in cats that spontaneously develop chronic kidney disease.