A Novel and Efficient Methodology for the Synthesis of Vinylamide Derivatives Using [Ce(L‐Pro)2]2Ox as Heterogeneous Catalyst. Issue 23 (20th June 2018)

• Record Type: Journal Article
• Authors: Tavares Junior, José M. C.; Silva, Caren D. G.; dos Santos, Beatriz F.; da Silva, Beatriz A. L.; de Oliveira, Aline R.; Kupfer, Vicente L.; Rinaldi, Andrelson W.; Domingues, Nelson Luís C.
• Is Part Of: ChemistrySelect. Volume 3:Issue 23(2018)
• Page Start: 6570
• Page End: 6574
• Publication Date: 2018-06-20
• Subjects: arylvinylbenzamides -- azlactones -- cerium -- heterogeneous catalysis; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201800760
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: In this work, we presented a simple, efficient, scalable, and green methodology for the synthesis of arylvinylbenzamides using various anilines and azlactones with [Ce( L ‐Pro)2 ]2 Ox as heterogeneous catalyst under green conditions in a short reaction time obtained good to excellent yields. Abstract : In this work we propose a new, regioselective, scalable and efficient synthesis of arylvinylbenzamides using[Ce( L ‐Pro)2 ]2 Ox as heterogeneous catalyst under green conditions aiming to obtain an efficient route for potentially interesting compounds. The synthesis of arylvinylbenzamides was successfully obtained affording a series of compounds with good to excellent yields. A scale‐up synthesis was performed with good yield indicating that the procedure can be applied to industrial processes.