A Case of mistaken identity: Rhabdomyosarcoma development from endothelial progenitor cells. (4th July 2018)
- Record Type:
- Journal Article
- Title:
- A Case of mistaken identity: Rhabdomyosarcoma development from endothelial progenitor cells. (4th July 2018)
- Main Title:
- A Case of mistaken identity: Rhabdomyosarcoma development from endothelial progenitor cells
- Authors:
- Drummond, Catherine J.
Hatley, Mark E. - Abstract:
- ABSTRACT: Rhabdomyosarcoma (RMS) histologically resembles developing skeletal muscle and is thought to solely originate from a differentiation block in muscle progenitors. We demonstrate that RMS can arise from endothelial progenitor cells following reprogramming and myogenic transdifferentiation. These results highlight how tumors with identical morphological features can arise from different cell types and offer insight into RMS formation in non-myogenic tissue.
- Is Part Of:
- Molecular & cellular oncology. Volume 5:Number 4(2018)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 5:Number 4(2018)
- Issue Display:
- Volume 5, Issue 4 (2018)
- Year:
- 2018
- Volume:
- 5
- Issue:
- 4
- Issue Sort Value:
- 2018-0005-0004-0000
- Page Start:
- Page End:
- Publication Date:
- 2018-07-04
- Subjects:
- cell of origin -- endothelial -- hedgehog -- muscle -- pediatric cancer -- reprogramming -- rhabdomyosarcoma -- skeletal muscle -- sarcoma -- transdifferentiation
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2018.1448246 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 9278.xml