Osteoporosis risk factors and bone microstructure evaluation: a population breakdown. (2018)

• Record Type: Journal Article
• Authors: Cosmi, Francesca; Nicolosi, Alessandra; Zatta, Giorgio
• Is Part Of: Materials today. Volume 5:Number 13(2018)Part 2
• Page Start: 26772
• Page End: 26777
• Publication Date: 2018
• Subjects: Osteoporosis -- Bone -- Trabecular bone -- Bone quality -- Bone Structure Index; Materials science -- Congresses -- Periodicals; 620.1
• DOI: 10.1016/j.matpr.2018.08.150
• Languages: English
• ISSNs: 2214-7853

Abstract

Abstract: Osteoporosis is a silent disease, characterized by a decreasing bone strength, which leads to a progressive increase in fracture risk. As mean average human lifespan is growing, a parallel rise in the rate of osteoporosis is observed. Currently, diagnosis is made on the basis of bone mineral density, which seems to be a poor fracture predictor in about 40-50% of cases, and of clinical risk factors, but the trabecular structure arrangement should be evaluated as well. The BSI (Bone Structure Index) is a new index computed from simulated application of loads on a virtual biopsy of the patient. In this work, we aim to identify the distributions of BSI and of fragility fracture risk factors recognized by the scientific community in a population of over 300 female volunteers.