Radical-clock α-halo-esters as mechanistic probes for bisphosphine iron-catalyzed cross-coupling reactions. Issue 2 (11th January 2019)
- Record Type:
- Journal Article
- Title:
- Radical-clock α-halo-esters as mechanistic probes for bisphosphine iron-catalyzed cross-coupling reactions. Issue 2 (11th January 2019)
- Main Title:
- Radical-clock α-halo-esters as mechanistic probes for bisphosphine iron-catalyzed cross-coupling reactions
- Authors:
- Liu, Lei
Lee, Wes
Zhou, Jun
Bandyopadhyay, Surjo
Gutierrez, Osvaldo - Abstract:
- Abstract: The mechanism of chiral bisphosphine iron-catalyzed C(sp 2 )-C(sp 3 ) cross-coupling reactions has been studied via the synthesis of novel radical-clock α-halo-esters and quantum mechanical calculations. These results provide insights into the role of the substrate (halogen and substituents) in competing in-cage and out-of-cage arylation pathways and provide a basis for the future rational design of novel tandem cyclization-arylation reactions using bisphosphine-iron as catalysts. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 75:Issue 2(2019)
- Journal:
- Tetrahedron
- Issue:
- Volume 75:Issue 2(2019)
- Issue Display:
- Volume 75, Issue 2 (2019)
- Year:
- 2019
- Volume:
- 75
- Issue:
- 2
- Issue Sort Value:
- 2019-0075-0002-0000
- Page Start:
- 129
- Page End:
- 136
- Publication Date:
- 2019-01-11
- Subjects:
- Tandem cyclization-arylation reactions -- Bisphosphine-iron -- Cross-coupling reactions -- Mechanisms -- DFT
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2018.11.043 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 9272.xml