Milestones in stereotactic radiosurgery for the central nervous system. (January 2019)

• Record Type: Journal Article
• Authors: Mitrasinovic, Stefan; Zhang, Michael; Appelboom, Geoff; Sussman, Eric; Moore, Justin M.; Hancock, Steven L.; Adler, John R.; Kondziolka, Douglas; Steinberg, Gary K.; Chang, Steven D.
• Is Part Of: Journal of clinical neuroscience. Volume 59(2019)
• Page Start: 12
• Page End: 19
• Publication Date: 2019-01
• Subjects: Stereotactic radiosurgery -- Intracranial metastases -- Meningioma -- Glioblastoma -- Behavioral disorders -- Arteriovenous malformation -- Trigeminal neuralgia -- Acoustic neuroma; Brain -- Surgery -- Periodicals; Neurosciences -- Periodicals; Nervous system -- Surgery -- Periodicals; Brain -- surgery -- Periodicals; Neurosurgical Procedures -- Periodicals; Neurosciences -- Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.jocn.2018.09.029
• Languages: English
• ISSNs: 0967-5868

Abstract

Highlights: SRS studies on intracranial metastases have become increasingly more sophisticated. Greater influence corresponded with higher quality RCTs and larger cohorts. AVM and acoustic neuroma are frequently-reported and well-established SRS subtopics. Spinal metastases and meningioma have more recently yielded influential works. Abstract: Introduction: Since Lars Leksell developed the first stereotactic radiosurgery (SRS) device in 1951, there has been growth in the technologies available and clinical indications for SRS. This expansion has been reflected in the medical literature, which is built upon key articles and institutions that have significantly impacted SRS applications. Our aim was to identify these prominent works and provide an educational tool for training and further inquiry. Method: A list of search phrases relating to central nervous system applications of stereotactic radiosurgery was compiled. A topic search was performed using PubMed and Scopus databases. The journal, year of publication, authors, treatment technology, clinical subject, study design and level of evidence for each article were documented. Influence was proposed by citation count and rate. Results: Our search identified a total of 10, 211 articles with the top 10 publications overall on the study of SRS spanning 443–1313 total citations. Four articles reported on randomized controlled trials, all of which evaluated intracranial metastases. The most prominent subtopics included SRS for arteriovenous malformation, glioblastoma, and acoustic neuroma. Greatest representation by treatment modality included Gamma Knife, LINAC, and TomoTherapy. Conclusions: This systematic reporting of the influential literature on SRS for intracranial and spinal pathologies underscores the technology's rapid and wide reaching clinical applications. Moreover the findings provide an academic guide to future health practitioners and engineers in their study of SRS for neurosurgery.