Advances in the synthesis of non-annelated polynuclear heterocyclic systems comprising the 1, 2, 5-oxadiazole ring. (October 2016)

• Record Type: Journal Article
• Authors: Fershtat, Leonid L.; Makhova, Nina N.
• Is Part Of: Russian chemical reviews. Volume 85:Number 10(2016)
• Page Start: 1097
• Page End: 1145
• Publication Date: 2016-10
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1070/RCR4619
• Languages: English
• ISSNs: 0036-021X

Abstract

Abstract : This review is concerned with recently developed synthetic methods for non-annelated polynuclear heterocyclic systems that incorporate, along with a furazan and(or) furoxan ring, polynitrogen and nitrogen – oxygen heterocycles (1, 2, 4- and 1, 3, 4-oxadiazole, 1, 2, 3- and 1, 2, 4-triazole, tetrazole, pyrazole, sym -triazine, 1, 2, 4, 5-tetrazine and so on) linked via C–C or C–N bonds or heteroatomic bridges. Methods for preparing assemblies in which a furazan ring and(or) a furoxan ring are linked to one another by C–C bonds or heteroatoms (N, O, S) are surveyed. Potential applications of the synthesized structures as pharmacologically active and high-energy compounds are discussed. The bibliography includes 266 references.