Urine Collection Method for the Diagnosis of Congenital Cytomegalovirus Infection. Issue 8 (August 2015)

• Record Type: Journal Article
• Authors: Ross, Shannon A.; Ahmed, Amina; Palmer, April L.; Michaels, Marian G.; Sánchez, Pablo J.; Stewart, Audra; Bernstein, David I.; Feja, Kristina; Novak, Zdenek; Fowler, Karen B.; Boppana, Suresh B.
• Is Part Of: Pediatric infectious disease journal. Volume 34:Issue 8(2015)
• Publication Date: 2015-08
• Subjects: cytomegalovirus -- urine -- cotton -- collection; Communicable diseases in children -- Periodicals; Infection in children -- Periodicals; 618.929
• DOI: 10.1097/INF.0000000000000757
• Languages: English
• ISSNs: 0891-3668

Abstract

Abstract : Congenital cytomegalovirus infection is traditionally diagnosed by virus detection in saliva or urine. Virus culture was positive in significantly fewer urine samples collected using cotton balls in diapers (55.2%) than with samples collected by bags (93.2%) from newborns screened positive for CMV in saliva. However, polymerase chain reaction was positive in 95% of urine samples regardless of the collection method.