Regioselective Oxidative Homocoupling Reaction: An Efficient Copper‐Catalyzed Synthesis of Biimidazo[1, 2‐a]pyridines. Issue 14 (25th September 2015)

• Record Type: Journal Article
• Authors: Lei, Sai; Cao, Hua; Chen, Longbin; Liu, Jingyun; Cai, Huiyin; Tan, Jingwen
• Is Part Of: Advanced synthesis & catalysis. Volume 357:Issue 14/15(2015)
• Page Start: 3109
• Page End: 3114
• Publication Date: 2015-09-25
• Subjects: biimidazo[1, 2‐a]pyridines -- CC bond formation -- copper catalysis -- homocoupling -- imidazo[1, 2‐a]pyridines; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201500391
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A facile and efficient copper(I)‐catalyzed intermolecular direct CH homocoupling of imidazo[1, 2‐ a ]pyridines with excellent C‐3 regioselectivity in dimethyl sulfoxide (DMSO) has been developed. This transformation provides a straightforward and operationally simple route for the preparation of biimidazo[1, 2‐ a ]pyridines which are an important structural motif in natural products and pharmaceuticals. Abstract :