Transcranial direct current stimulation of dorsolateral prefrontal cortex during encoding improves recall but not recognition memory. (November 2017)

• Record Type: Journal Article
• Authors: Leshikar, Eric D.; Leach, Ryan C.; McCurdy, Matthew P.; Trumbo, Michael C.; Sklenar, Allison M.; Frankenstein, Andrea N.; Matzen, Laura E.
• Is Part Of: Neuropsychologia. Volume 106(2017)
• Page Start: 390
• Page End: 397
• Publication Date: 2017-11
• Subjects: Brain stimulation -- tDCS -- dlPFC -- Immediate effects of tDCS -- Delayed effects of tDCS -- Associative memory -- Recall -- Recognition -- Episodic memory; Neuropsychology -- Periodicals; Neurology -- Periodicals; Psychophysiology -- Periodicals; Neuropsychologie -- Périodiques; Neuropsychology; Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.neuropsychologia.2017.10.022
• Languages: English
• ISSNs: 0028-3932

Abstract

Abstract: Prior work demonstrates that application of transcranial direct current stimulation (tDCS) improves memory. In this study, we investigated tDCS effects on face-name associative memory using both recall and recognition tests. Participants encoded face-name pairs under either active (1.5 mA) or sham (.1 mA) stimulation applied to the scalp adjacent to the left dorsolateral prefrontal cortex (dlPFC), an area known to support associative memory. Participants' memory was then tested after study (day one) and then again after a 24-h delay (day two), to assess both immediate and delayed stimulation effects on memory. Results indicated that active relative to sham stimulation led to substantially improved recall (more than 50%) at both day one and day two. Recognition memory performance did not differ between stimulation groups at either time point. These results suggest that stimulation at encoding improves memory performance by enhancing memory for details that enable a rich recollective experience, but that these improvements are evident only under some testing conditions, especially those that rely on recollection. Overall, stimulation of the dlPFC could have led to recall improvement through enhanced encoding from stimulation or from carryover effects of stimulation that influenced retrieval processes, or both. Highlights: tDCS effects on associative memory were measured by recall and recognition tests. Memory was measured both immediately after stimulation and after a 24 h delay. tDCS-induced memory improvement was evident in recall, but not recognition. Recall improvement was apparent both immediately after stimulation and after delay.