Incidence, prevalence, mortality, disability-adjusted life years and risk factors of cancer in Australia and comparison with OECD countries, 1990–2015: findings from the Global Burden of Disease Study 2015. (February 2018)

• Record Type: Journal Article
• Authors: Melaku, Yohannes Adama; Appleton, Sarah L.; Gill, Tiffany K.; Ogbo, Felix A.; Buckley, Elizabeth; Shi, Zumin; Driscoll, Tim; Adams, Robert; Cowie, Benjamin C.; Fitzmaurice, Christina
• Is Part Of: Cancer epidemiology. Volume 52(2018:Feb.)
• Page Start: 43
• Page End: 54
• Publication Date: 2018-02
• Subjects: Burden of disease -- Cancer -- Burden of cancer -- Cancer risk factors -- Australia -- Oecd; Cancer -- Epidemiology -- Periodicals; Cancer -- Prevention -- Periodicals; Cancer -- Diagnosis -- Periodicals; Carcinogenesis -- Periodicals; 616.994005
• DOI: 10.1016/j.canep.2017.11.007
• Languages: English
• ISSNs: 1877-7821

Abstract

Highlights: In Australia, the age-standardized cancer incidence rate (ASIR) increased while the death rate (ASDR) decreased (1990–2015). In 2015, out of 35 OECD countries, Australia ranked 1 st (highest) and 24 th based on the ASIR and ASDR respectively. Thirty-six percent of cancer deaths in Australia are attributable to behavioural risk factors. Abstract: Background: Comparative evidence on the burden, trend, and risk factors of cancer is limited. Using data from the Global Burden of Disease (GBD) study, we aimed to assess cancer burden – incidence, prevalence, mortality, disability-adjusted life years (DALYs) – and attributable risk factors for Australia between 1990 and 2015, and to compare them with those of 34 members of the Organisation for Economic Co-operation and Development (OECD). Methods: The general GBD cancer estimation methods were used with data input from vital registration systems and cancer registries. A comparative risk assessment approach was used to estimate the population-attributable fractions due to risk factors. Results: In 2015 there were 198, 880 (95% uncertainty interval [UI]: 183, 908–217, 365) estimated incident cancer cases and 47, 562 (95% UI: 46, 061–49, 004) cancer deaths in Australia. Twenty-nine percent (95% UI: 28.2–29.8) of total deaths and 17.0% (95% UI: 15.0–19.1) of DALYs were caused by cancer in Australia in 2015. Cancers of the trachea, bronchus and lung, colon and rectum, and prostate were the most common causes of cancer deaths. Thirty-six percent (95% UI: 33.1–37.9) of all cancer deaths were attributable to behavioral risks. The age-standardized cancer incidence rate (ASIR) increased between 1990 and 2015, while the age-standardized cancer death rate (ASDR) decreased over the same period. In 2015, compared to 34 other OECD countries Australia ranked first (highest) and 24 th based on ASIR and ASDR, respectively. Conclusion: The incidence of cancer has increased over 25 years, and behavioral risks are responsible for a large proportion of cancer deaths. Scaling up of prevention (using strategies targeting cancer risk factors), early detection, and treatment of cancer is required to effectively address this growing health challenge.