One‐Pot Synthesis of 6‐Aminopyrido[2, 3‐d]pyrimidin‐7‐ones. Issue 46 (25th November 2018)

• Record Type: Journal Article
• Authors: Zinchenko, Anna M.; Muzychka, Lyubov V.; Kucher, Olexandr V.; Sadkova, Iryna V.; Mykhailiuk, Pavel K.; Smolii, Oleg B.
• Is Part Of: European journal of organic chemistry. Issue 46(2018)
• Page Start: 6519
• Page End: 6523
• Publication Date: 2018-11-25
• Subjects: Heterocycles -- Amines -- One‐pot synthesis -- Drug design; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201801204
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : One‐pot synthesis of 6‐aminopyrido[2, 3‐ d ]pyrimidin‐7‐ones from 4‐aminopyrimidine‐5‐carbaldehydes and the in situ N ‐protected methyl glycinate is developed. The obtained compounds have a polyfunctional character and provide opportunities for their use in drug design projects. Abstract : One‐pot synthesis of 6‐aminopyrido[2, 3‐ d ]pyrimidin‐7‐ones from 4‐aminopyrimidine‐5‐carbaldehydes and the in situ N ‐protected methyl glycinate is developed. The obtained compounds have a polyfunctional character and provide opportunities for use in drug design.