AKIN10 activity as a cellular link between metabolism and circadian-clock entrainment in Arabidopsis thaliana. (4th March 2018)

• Record Type: Journal Article
• Authors: Sánchez-Villarreal, Alfredo; Davis, Amanda M.; Davis, Seth J.
• Is Part Of: Plant signaling & behavior. Volume 13:Number 3(2018)
• Publication Date: 2018-03-04
• Subjects: Clock entrainment -- cellular homeostasis -- metabolic homeostasis -- light signaling -- clock period; Plant ecophysiology -- Periodicals; Plant cellular signal transduction -- Periodicals; Plant cellular signal transduction; Plant ecophysiology; Periodicals; Electronic journals; 581
• DOI: 10.1080/15592324.2017.1411448
• Languages: English
• ISSNs: 1559-2316

Abstract

ABSTRACT: AKIN10, the catalytic subunit of the Snf1 (sucrose non-fermenting 1)-related kinase 1 (SnRK1) complex, acts as an energy sensor in plants. We showed that AKIN10 -induced expression affects the pace of the circadian clock and particularly the phase of expression of GIGANTEA (GI) . The AKIN10 effect on period length required TIME FOR COFFEE ( TIC ), a circadian-clock component with developmental and metabolic roles. Here we expand on the possible interactions between AKIN10, whose activity is involved in transcriptional reprogramming, and clock elements GI and TIC . We hypothesize how they could participate in clock entrainment through a metabolic signal derived from carbon pools and starch metabolism. Additionally, we consider further the role of cellular energy status to the clock through the formation of a hypothetical protein complex. We also demonstrate the role of AKIN10, but not its sequence-related kinase AKIN11, on clock periodicity. Altogether we present a model of action of these elements in metabolic-related clock entrainment.