Resveratrol has not been proven its enhancement of the physical activity among users: A systematic review and meta-analysis study. (July 2018)

• Record Type: Journal Article
• Authors: Srilacorn, Chainarong; Choosathan, Apisada; Seesuthok, Siriporn; Kongna, Somsak; Kotirum, Surachai
• Is Part Of: Journal of functional foods. Volume 46(2018)
• Page Start: 475
• Page End: 481
• Publication Date: 2018-07
• Subjects: Resveratrol -- Physical activity -- Stilbenoid -- Phytoalexin -- Systematic review -- Meta-analysis; Functional foods -- Analysis -- Periodicals; Food -- Biotechnology -- Periodicals; Nutrition -- Periodicals; 613.2
• DOI: 10.1016/j.jff.2018.05.022
• Languages: English
• ISSNs: 1756-4646

Abstract

Graphical abstract: Highlights: Resveratrol slightly improves physical activity from current evidence in humans. Insignificant physical activity improvement when comparing resveratrol to placebo. Young resveratrol users may get benefit on physical activity more than elderly. Larger subjects needed for next clinical trials of resveratrol on physical activity. Abstract: Current evidence of resveratrol on physical activity were summarized using a systematic review and meta-analysis approach. Fourteen randomized controlled trials met the eligibility criteria. All included studies enrolled a few subjects. Five studies with 139 participants measured the same outcome and then were pooled using the meta-analysis program. The mean change between pre- and post-test when compared resveratrol to control on the peak oxygen uptake outcome is 0.30 mL/kg/min (−2.49 to 3.09). This meta-analysis results showed that resveratrol slightly increases a surrogate outcome of physical activity. However, the increment was not achieved minimally clinical significance of at least 2 mL/kg/min. In summary, resveratrol slightly improves one indicator of physical activity, but did not demonstrate statistical and clinical significances. However, these combined results were drawn out from multiple studies with small participants. Therefore, rigorous efficacy trials in large subjects are still warranted to ensure the effect of resveratrol on physical activity.