Biocompatibility and in vivo operation of implantable mesoporous PVDF-based nanogenerators. (September 2016)

• Record Type: Journal Article
• Authors: Yu, Yanhao; Sun, Haiyan; Orbay, Hakan; Chen, Feng; England, Christopher G.; Cai, Weibo; Wang, Xudong
• Is Part Of: Nano energy. Volume 27(2016:Sep.)
• Page Start: 275
• Page End: 281
• Publication Date: 2016-09
• Subjects: Biocompatibility -- In vivo biomechanical energy harvesting -- Mesoporous PVDF -- Piezoelectric nanogenerator; Nanoscience -- Periodicals; Nanotechnology -- Periodicals; Nanostructured materials -- Periodicals; Power resources -- Technological innovations -- Periodicals; Nanoscience; Nanostructured materials; Nanotechnology; Power resources -- Technological innovations; Periodicals; 621.042
• DOI: 10.1016/j.nanoen.2016.07.015
• Languages: English
• ISSNs: 2211-2855

Abstract

Abstract: The rapid developments of implantable biomedical electronics give rise to the motivation of exploring efficient and durable self-powered charging system. In this paper, we report a mesoporous polyvinylidene fluoride (PVDF)-based implantable piezoelectric nanogenerator (NG) for in vivo biomechanical energy harvesting. The NG was built with a sponge-like mesoporous PVDF film and encapsulated by polydimethylsiloxane (PDMS). After embedding this NG into rodents, a V oc of ~200 mV was produced from the gentle movement of rodent muscle. Meanwhile, no toxicity or incompatibility sign was found in the host after carrying the packaged NG for 6 weeks. Moreover, the electric output of this NG was extremely stable and exhibited no deterioration after 5 days of in vivo operation or 1.512×10 8 times mechanical deformation. This NG device could practically output a constant voltage of 52 mV via a 1 μF capacitor under living circumstance. The outstanding efficiency, magnificent durability and exceptional biocompatibility promise this mesoporous PVDF-based NG in accomplishing self-powered bioelectronics with potentially lifespan operation period. Graphical abstract: Highlights: Photographs of implanted PVDF nanogenerator inside a living mouse. In vivo voltage output of the packaged PVDF nanogenerator within 5 days operation.