Spontaneous Regression in a Patient With Infantile Fibrosarcoma. Issue 4 (May 2018)

• Record Type: Journal Article
• Authors: Sait, Sameer Farouk; Danzer, Enrico; Ramirez, Daniel; LaQuaglia, Michael P.; Paul, Meyers
• Is Part Of: Journal of pediatric hematology/oncology. Volume 40:Issue 4(2018)
• Publication Date: 2018-05
• Subjects: spontaneous regression -- infantile fibrosarcoma -- surgery; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000001013
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : Infantile fibrosarcoma usually presents as a rapidly growing mass on the extremities or trunk. We describe spontaneous regression in a 5-month-old female infant with biopsy proven, molecularly confirmed, right leg infantile fibrosarcoma currently at 26 months of age with no signs of local recurrence. Previously reported cases of spontaneous regression are reviewed, suggesting a benign clinical course in some cases. Although evidence for spontaneous regression is anecdotal in this rare tumor type, physicians should weigh the risks and benefits of surgery and chemotherapy against watchful waiting.