Cover Feature: Two‐Photon Fluorescence Imaging and Therapy of Cancer Cells with Anisotropic Gold‐Nanoparticle‐Supported Porous Silicon Nanostructures (ChemNanoMat 4/2018). Issue 4 (15th March 2018)

• Record Type: Journal Article
• Authors: Chaix, Arnaud; Rajoua, Khalil; Stojanovic, Vanja; El Cheikh, Khaled; Bouffard, Elise; Brocéro, Anthony; Garcia, Marcel; Maynadier, Marie; Morère, Alain; Gary‐Bobo, Magali; Favier, Frédéric; Durand, Jean‐Olivier; Cunin, Frédérique
• Is Part Of: ChemNanoMat. Volume 4:Issue 4(2018)
• Page Start: 318
• Page End: 318
• Publication Date: 2018-03-15
• Subjects: gold -- nanoparticles -- photodynamic therapy -- silicon -- targeting agent -- two-photon imaging; Nanochemistry -- Periodicals; Nanostructured materials -- Periodicals; Nanochemistry; Nanostructured materials; Periodicals; 541.2
• DOI: 10.1002/cnma.201800080
• Languages: English
• ISSNs: 2199-692X

Abstract

Abstract : Porous silicon nanovectors carrying gold nanoparticles and functionalized with mannose species as tumor targeting agents demonstrate remarkable capability as 2‐photon imaging contrast agents. An important photodynamic efficiency of the nanovectors is also observed in human breast cancer cells, with the formation of reactive oxygen species when exposed to two‐photon light excitation. Such targeted porous silicon/gold nanovectors provide an interesting opportunity for 2‐photon imaging and for photodynamic therapy, and an interesting potential for theranostic applications. More information can be found in the Communication by Frédérique Cunin et al. onpage 343 in Issue 4, 2018 (DOI:10.1002/cnma.201700368 ).