Cover Picture: Enolate Stabilization by Anion–π Interactions: Deuterium Exchange in Malonate Dilactones on π‐Acidic Surfaces (Chem. Eur. J. 8/2016). Issue 8 (11th February 2016)

• Record Type: Journal Article
• Authors: Miros, François N.; Zhao, Yingjie; Sargsyan, Gevorg; Pupier, Marion; Besnard, Céline; Beuchat, César; Mareda, Jiri; Sakai, Naomi; Matile, Stefan
• Is Part Of: Chemistry. Volume 22:Issue 8(2016)
• Page Start: 2541
• Page End: 2541
• Publication Date: 2016-02-11
• Subjects: acidity -- anion–π interactions -- deuterium exchange -- enolates -- macrocycles -- stereoselectivity; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201680801
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract : The crystal structure of a malonate dilactone, placed on the π‐acidic surface of a naphthalenediimide with chiral sulfoxide acceptors in the core, is depicted on the cover. Such macrodilactones are essential to directly follow enolate–π interactions by NMR spectroscopy, also during deuterium exchange. This least interfering method is used to extract all there is to learn about the stabilization of enolate intermediates and transition states on π‐acidic aromatic surfaces. More information can be found in the Full Paper by S. Matile et al. onpage 2648 ff.