Cover Picture: Pillar[5]arene‐Based Glycoclusters: Synthesis and Multivalent Binding to Pathogenic Bacterial Lectins (Chem. Eur. J. 9/2016). Issue 9 (11th February 2016)

• Record Type: Journal Article
• Authors: Buffet, Kevin; Nierengarten, Iwona; Galanos, Nicolas; Gillon, Emilie; Holler, Michel; Imberty, Anne; Matthews, Susan E.; Vidal, Sébastien; Vincent, Stéphane P.; Nierengarten, Jean‐François
• Is Part Of: Chemistry. Volume 22:Issue 9(2016)
• Page Start: 2833
• Page End: 2833
• Publication Date: 2016-02-11
• Subjects: click chemistry -- cycloadditions -- glycoconjugates -- ligand effects -- medicinal chemistry; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201600405
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract : The potential therapeutic applications of multivalent glycoclusters targeting bacterial adhesion lectins call for the design of core scaffolds presenting various valency and topologies to understand the specificities of binding. Pillar[5]arenes are ideal candidates in this endeavor. More information can be found in the Full Paper by A. Imberty, S. Vidal, S. P. Vincent, J.‐F. Nierengarten, et al. onpage 2955 ff.