Advances in Carbon Nanotubes–Hydrogel Hybrids in Nanomedicine for Therapeutics. Issue 9 (1st February 2018)

• Record Type: Journal Article
• Authors: Vashist, Arti; Kaushik, Ajeet; Vashist, Atul; Sagar, Vidya; Ghosal, Anujit; Gupta, Y. K.; Ahmad, Sharif; Nair, Madhavan
• Is Part Of: Advanced healthcare materials. Volume 7:Issue 9(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-02-01
• Subjects: biomaterials -- biosensors -- carbon nanotubes -- drug delivery -- hydrogel hybrids -- imaging systems -- tissue engineering; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201701213
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract: In spite of significant advancement in hydrogel technology, low mechanical strength and lack of electrical conductivity have limited their next‐level biomedical applications for skeletal muscles, cardiac and neural cells. Host–guest chemistry based hybrid nanocomposites systems have gained attention as they completely overcome these pitfalls and generate bioscaffolds with tunable electrical and mechanical characteristics. In recent years, carbon nanotube (CNT)‐based hybrid hydrogels have emerged as innovative candidates with diverse applications in regenerative medicines, tissue engineering, drug delivery devices, implantable devices, biosensing, and biorobotics. This article is an attempt to recapitulate the advancement in synthesis and characterization of hybrid hydrogels and provide deep insights toward their functioning and success as biomedical devices. The improved comparative performance and biocompatibility of CNT–hydrogels hybrids systems developed for targeted biomedical applications are addressed here. Recent updates toward diverse applications and limitations of CNT hybrid hydrogels is the strength of the review. This will provide a holistic approach toward understanding of CNT‐based hydrogels and their applications in nanotheranostics. Abstract : Host‐guest chemistry based organic‐inorganic nanocomposites composed of 3D hydrogel and carbon nanotubes (CNTs) have revolutionized the hydrogel/CNTs technologies with improved performance in the area of regenerative medicine, tissue engineering, targeted drug delivery, implantable devices, bio‐sensing and bio‐robotics. This review highlights the synthesis of CNT hybrid hydrogels and provides the recent updates on CNTs‐hydrogel hybrid systems and their biomedical applications.