Microwave‐assisted Synthesis of Dihydro Dibenzophenanthroline and Its Derivatives Using a Self‐catalyzed Friedlander Reaction. (18th October 2018)

• Record Type: Journal Article
• Authors: Chandraprakash, Kumarasamy; Vandana, Nandakumar; Sankaran, Mathan; Uvarani, Chokkalingam; Ata, Athar; Mohan, Palathurai Subramaniam; Suresh, Thangaraj
• Is Part Of: Journal of heterocyclic chemistry. Volume 55:Number 12(2018)
• Page Start: 2766
• Page End: 2771
• Publication Date: 2018-10-18
• Subjects: Heterocyclic compounds -- Periodicals; 547.59
• DOI: 10.1002/jhet.3339
• Languages: English
• ISSNs: 0022-152X

Abstract

Abstract : One‐step microwave‐assisted synthesis of dihydro dibenzophenanthrolines are reported using a self‐catalyzed Friedlander reaction. The reaction is carried out in one step by simple microwave irradiation of 3, 4‐dihydroacridin‐1(2 H )‐one with 2‐amino‐benzophenone in the presence of acid catalysts with solvent‐free conditions. Thin‐layer chromatography was used to monitor the progress of the reaction; hence, it was observed that the reaction starts slowly and accelerates as it proceeds to ring fusion transformation. Synthesized compounds' isolated yield is enhanced in the absence of solvent systems with Friedlander catalyst under microwave irradiations. Abstract :