A multi‐parametric PET/MRI study of breast cancer: Evaluation of DCE‐MRI pharmacokinetic models and correlation with diffusion and functional parameters. (31st October 2018)

• Record Type: Journal Article
• Authors: Inglese, Marianna; Cavaliere, Carlo; Monti, Serena; Forte, Ernesto; Incoronato, Mariarosaria; Nicolai, Emanuele; Salvatore, Marco; Aiello, Marco
• Is Part Of: NMR in biomedicine. Volume 32:Number 1(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-10-31
• Subjects: breast cancer -- DCE‐MRI -- diffusion imaging -- PET/MR -- pharmacokinetic models -- shutter speed model -- Tofts model; Nuclear magnetic resonance -- Periodicals; Magnetic Resonance Spectroscopy -- Periodicals; 574
• DOI: 10.1002/nbm.4026
• Languages: English
• ISSNs: 0952-3480

Abstract

Abstract : 46 patients with histologically confirmed breast cancer were enrolled and imaged with a 3T hybrid PET/MRI system, at staging. Diffusion, functional and perfusion parameters (measured by Tofts and shutter speed models) were compared. Results showed a good correlation between pharmacokinetic parameters and the SUV.