Conversion of aldimines to secondary amines using iron-catalysed hydrosilylation. Issue 48 (5th December 2018)

• Record Type: Journal Article
• Authors: Saini, Anu; Smith, Cecilia R.; Wekesa, Francis S.; Helms, Amanda K.; Findlater, Michael
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 48(2018)
• Page Start: 9368
• Page End: 9372
• Publication Date: 2018-12-05
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c8ob01262h
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : Hydrosilylation of imines was achieved using a redox non-innocent Fe-BIAN catalyst and employing the inexpensive trialkoxysilane (EtO)3 SiH. Abstract : Iron-catalyzed hydrosilylation of imines to amines using a well-defined iron complex is reported. This method employs relatively mild conditions, by reaction of imine, (EtO)3 SiH in a 1 : 2 ratio in the presence of 1 mol% precatalyst ([BIAN]Fe(η 6 -toluene), 3, BIAN = bis(2, 6-diisopropylaniline)acenaphthene) at 70 °C. A broad scope of imines was readily converted into the corresponding secondary amines without the need for precatalyst activators.